Chemical Synthetic Platform for Chlorpromazine Oligomers That Were Reported as Photo-degradation Products of Chlorpromazine
نویسندگان
چکیده
منابع مشابه
Central actions of chlorpromazine.
It was synthesized by M/s Rhone Poulence Laboratories of Paris, to meet the demand for a drug that will be effective in the prcvention and/or treatment of surgical shock, This was sought to be achicved by damping out the homeostalic regulating reactions including those under the control of the hypothalamus, by Ihe use of a suitable pharmacodynamic agent, supplemented by induced hypothermia. CPZ...
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Major use Chlorpromazine hydrochloride (CPH) belongs to antipsychotic drugs, also called neuroleptics; and it is mainly used for the treatment of neurological disorders. CPH has sedative, hypotensive and antiemetic properties. CPH, which is an aliphatic phenothiazine, was first synthesized in 1952. It was extensively studied and used as a model for a big class of neuroleptic agents. Haloperidol...
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In view of the possibility of human error or changes in our knowledge due to continued research, neither the author nor The University of Iowa nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they are not responsible for any errors or omissions or for the results ...
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Forty-four hospitalized schizophrenic patients, 22 in each of two groups, were treated for a period of 6 weeks with either EGT-GPZ combination or CPZ alone. Ratings on RP scale (Rockland and Pollin, 1S65) showed that the KGT-receiving group was significantly better en several measure at second week and also had an earlier onset of beneficial response on "Affect and Mood." However, at the end of...
متن کاملChlorpromazine in ocular surgery.
IN INDLA cataract surgery is a major problem. We consider any person above 60 years of age as a potential cataract patient if he is not one already. Through lack of education, the cooperation of the patient in intra-ocular surgery is not all one would like it to be, and it is therefore best not to rely on the patient's cooperation but to administer suitable sedatives. Chlorpromazine promises to...
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ژورنال
عنوان ژورنال: CHEMICAL & PHARMACEUTICAL BULLETIN
سال: 2017
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c17-00692